The treatment entails injecting polynucleotides, which are DNA fragments from trout or salmon sperm, into one’s skin.
It is supposed that because fish DNA is similar to human DNA, the latter may welcome the former and trigger the production of collagen and elastin-two very important skin proteins for firmness and elasticity.
-They hope that acne scars, redness, fine lines, and wrinkles will be reduced.
-Celebrities like Charli XCX, the Kardashians, and Jennifer Aniston mention “salmon sperm facials,” boosting popularity.
-Treatments cost £200–£500 per session, with multiple sessions and regular top‑ups recommended.
-Some customers report fresher, more hydrated, youthful skin.
-Clinics say demand has surged in the past 18 months.
-Early studies have indicated great potential for skin rejuvenation, but the evidence so far is limited.
-It can produce side effects, including redness, swelling, bruising, and pigmentation problems if injected incorrectly.
-Allergic reactions and infections can occur.
-Regulation is inconsistent:
.In the UK, polynucleotides are registered as medical devices and not as drugs.
.Within the US, they are not approved by the FDA.
-Dermatologists caution that marketing may be running ahead of science. Large, long‑term studies are still lacking.
For other patients, such as New York’s Charlotte Bickley, the results were worse: swelling, dark circles, and post-treatment marks that lasted. Others, like Abby from Manchester, were pleased, claiming their skin looked healthier and fresher. Expert Opinions Professionals agree polynucleotides are not the miraculous cure. They may help some patients seeking a natural look, but results vary widely. Key factors are regulation and product quality- unverified brands pose risks.
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